Talent:

Glyphs:Howling Blast +FrostStrikes+Obliterate

The mode：

Single plague

Start with a Howling Blast

then Obliterate+Blood Strike+Blood Strike+FrostStrikes*n+Obliterate*3+FrostStrikes*n......

Now here's the key point

with three macros below we could made the skill casted with only one key.

Three macro:

Macor1

#showtooltip c

/console Sound_EnableSFX 0

/startattack

/cast runic blast

/castrandom Howling Blast , Howling Blast , Howling Blast , Howling Blast , Obliterate

/script UIErrorsFrame:Clear()

/console Sound_EnableSFX 1

Macro2

/console Sound_EnableSFX 0

/castsequence reset=16 Blood Strike, Blood Strike, Obliterate, Obliterate, Howling Blast

/script UIErrorsFrame:Clear()

/console Sound_EnableSFX 1

Macor3

#showtooltip FrostStrikes

/console Sound_EnableSFX 0

/castrandom Howling Blast , FrostStrikes

/script UIErrorsFrame:Clear()

/console Sound_EnableSFX 1

Put these three in the button 1,7,8


Put the Howling Blast in an separate key and you can just push 1 after Howling Blast